Skip to product information
1 of 6

Supreme Joints

Supreme Joints

Regular price $19.99
Regular price Sale price $19.99
Sale Sold out
Tax included.
  • Comprehensive joint support*
  • Promotes joint health*
  • Supports cartilage and ligaments*
  • Supports mobility and flexibility*
  • Efficient long-term support formula
View full details

Take 2 tablets twice a day.

Do not take if you are pregnant or breastfeeding. Consult your physician before use if you have a medical condition or are taking any medication.


Other Ingredients: Microcrystalline cellulose, corn starch, coating (hydroxypropyl methylcellulose, titanium dioxide (color), glycerin), magnesium stearate (vegetable).

Efficient Long-Term Support Formula

Supreme Joints is advanced joint formula designed to support healthy joint structure1-4, function5-8 and mobility7,9-13 as we normally age.* Its nine ingredients, with their well-researched doses, form three complexes, which provide complete joint health support1,2,11-13,3-10.* The Joint Structure Complex supplies joints with building elements for their healthy structure1,2,4,14,15.* Joint Flex Complex is specially designed to help support joint flexibility and effortless movement12,13,19,20.* Joint Comfort Complex provides powerful extracts for joint comfort maintenance26-29.*



    Glucosamine is a natural building block and component found in connective tissue and joint cartilage. Scientific research has shown that Glucosamine helps in the support of the body’s natural ability to regenerate and lubricate joints, thus supporting joint health and function.*


    Hyaluronic acid is an important structural component of the fluids surrounding the joints. Hyaluronic acid has the capacity to hold water thus regulates moisture in the tissues and maintenance joint lubrication.*


    Boron plays an important role in the bone metabolism to help support the healthy structure of the underlying bone.*


    Vitamin C is a vitamin, which our body cannot produce by itself while it plays a key role for maintaining overall health.* Though vitamin C can be found in numerous fruits and vegetables, many people turn to supplements to guarantee the daily recommended intake. Known for its powerful antioxidant benefits, vitamin C is important for contributing to normal collagen formation for the normal function of cartilage.*


    Manganese is an essential trace element that is naturally present in seeds and whole grains, as well as in smaller amounts in legumes, beans, nuts, leafy green vegetables and tea. Many studies reported the necessity of manganese to support the normal functioning of our bodies.* Manganese is also known for contributing of normal bones and normal formation of connective tissue.*


    Avocado-soybean unsaponifiables (ASU) is a vegetable extract made from avocado and soybean oils. ASU support joint flexibility and smooth movements.* ASU supports the body's production of vital joint tissue components to maximize mobility.*


    Collagen type II, besides being a natural building block for the joint structures, helps strengthen joints and tendons providing better mobility and flexibility.* It has been shown in clinical studies that when it is non-denatured, Collagen type II supports the healthy balance of the immune system.*


    Cissus quadrangularis is a plant that is rich in vitamin C and antioxidants. Its traditional use comes from Ayurveda, but is used in many Asiatic countries. It includes bioactive constituents, that have been shown in scientific studies to affect key enzymes, involved in the maintenance of healthy tissues.* Through these mechanisms, it may help support the state of comfort in the joints through the typical wear and tear of everyday life.* Our extract of Cissus quadrangularis provide high concentration of ketosterones, which support optimum joint health and comfort.*


    Boswellia (also known as Indian frankincense) is a gum resin extracted from the Boswellia serrata tree. It is a traditional part of Ayurvedic, with documented application in Traditional Chinese herbalists and its usage has spread to the Middle East and other tropical regions. Boswellia serrata extract has a complex of boswellic acids, which interact with a number of enzymes involved in processes that are essential to maintaining normal joint health.* Boswellia serrata extract, which includes a proprietary boswellia oleoresin component, support joint health and function.*
  1. Noyszewski EA, Wroblewski K, Dodge GR, et al. Arthritis Rheum. 2001;44(5):1089-1095. doi:10.1002/1529-0131(200105)44:5<1089::AID-ANR189>3.0.CO;2-9
  2. Akmal M, Singh A, Anand A, et al. J Bone Joint Surg Br. 2005;87(8):1143-1149. doi:10.1302/0301-620X.87B8.15083
  3. Uitterlinden EJ, Koevoet JLM, Verkoelen CF, et al. BMC Musculoskelet Disord. 2008;9:120. doi:10.1186/1471-2474-9-120
  4. Scientific Opinion on the substantiation of health claims related to vitamin C and protection of DNA, proteins and lipids from oxidative damage (ID 129, 138, 143, 148), antioxidant function of lutein (ID 146), maintenance of vision (ID 141, 142), collagen. EFSA J. 2009. doi:10.2903/j.efsa.2009.1226
  5. Reginster JY, Deroisy R, Rovati LC, et al. Lancet (London, England). 2001;357(9252):251-256. doi:10.1016/S0140-6736(00)03610-2
  6. Henrotin Y, Chevalier X, Herrero-Beaumont G, et al. BMC Res Notes. 2013;6:115. doi:10.1186/1756-0500-6-115
  7. Appelboom T, Schuermans J, Verbruggen G, Henrotin Y, Reginster JY. Scand J Rheumatol. 2001;30(4):242-247.
  8. Pavelka K, Gatterova J, Olejarova M, Machacek S, Giacovelli G, Rovati LC. Arch Intern Med. 2002;162(18):2113-2123.
  9. Maheu E, Mazieres B, Valat JP, et al. Arthritis Rheum. 1998;41(1):81-91. doi:10.1002/1529-0131(199801)41:1<81::AID-ART11>3.0.CO;2-9
  10. Lequesne M, Maheu E, Cadet C, Dreiser R-L. Arthritis Rheum. 2002;47(1):50-58. doi:10.1002/art1.10239 [pii]
  11. Maheu E, Cadet C, Marty M, et al. Ann Rheum Dis. 2014;73(2):376-384. doi:10.1136/annrheumdis-2012-202485
  12. Crowley DC, Lau FC, Sharma P, et al. Int J Med Sci. 2009;6(6):312-321.
  13. Lugo JP, Saiyed ZM, Lau FC, et al. J Int Soc Sports Nutr. 2013;10(1):48. doi:10.1186/1550-2783-10-48
  14. Gandhi NS, Mancera RL. Chem Biol Drug Des. 2008;72(6):455-482. doi:10.1111/j.1747-0285.2008.00741.x
  15. Scientific Opinion on the substantiation of health claims related to manganese and reduction of tiredness and fatigue (ID 312), contribution to normal formation of connective tissue (ID 404) and contribution to normal energy yielding metabolism (ID 405) pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA J. 2010;8(10). doi:10.2903/j.efsa.2010.1808
  16. Devirian TA, Volpe SL. Crit Rev Food Sci Nutr. 2003;43(2):219-231. doi:10.1080/10408690390826491
  17. EFSA Panel on Dietetic Products N and A (NDA). EFSA J. 2010;7(1924):1-28. doi:10.2903/j.efsa.2009.1226.
  18. Scientific Opinion on the substantiation of health claims related to manganese and protection of DNA, proteins and lipids from oxidative damage (ID 309), maintenance of bone (ID 310), energy-yielding metabolism (ID 311), and cognitive function (ID 340) pu. EFSA J. 2009. doi:10.2903/j.efsa.2009.1217
  19. Blotman F, Maheu E, Wulwik A, Caspard H, Lopez A. Rev Rhum Engl Ed. 1997;64(12):825-834.
  20. Christiansen BA, Bhatti S, Goudarzi R, Emami S. Cartilage. 2015;6(1):30-44. doi:10.1177/1947603514554992
  21. Au RY, Al-Talib TK, Au AY, Phan P V, Frondoza CG. Osteoarthritis Cartilage. 2007;15(11):1249-1255. doi:10.1016/j.joca.2007.07.009
  22. Maheu E, Mazieres B, Valat JP, et al. Arthritis Rheum. 1998;41(1):81-91. doi:10.1002/1529-0131(199801)41:1<81::AID-ART11>3.0.CO;2-9
  23. Bagchi D, Misner B, Bagchi M, et al. Int J Clin Pharmacol Res. 2002;22(3-4):101-110.
  24. Lugo JP, Saiyed ZM, Lane NE. Nutr J. 2016;15:14. doi:10.1186/s12937-016-0130-8
  25. Barnett ML, Kremer JM, St Clair EW, et al. Arthritis Rheum. 1998;41(2):290-297. doi:10.1002/1529-0131(199802)41:2<290::AID-ART13>3.0.CO;2-R
  26. Bloomer RJ, Farney TM, McCarthy CG, Lee S-R. Phys Sportsmed. 2013;41(3):29-35. doi:10.3810/psm.2013.09.2021
  27. Vishal AA, Mishra A, Raychaudhuri SP. Int J Med Sci. 2011;8(7):615-622.
  28. Sengupta K, Krishnaraju A V, Vishal AA, et al. Int J Med Sci. 2010;7(6):366-377.
  29. Nie TW, Shukkoor MSA, Nair RS, Amiruddin FKB, Ramasamy S. J Basic Clin Physiol Pharmacol. 2015;26(1):35-41. doi:10.1515/jbcpp-2014-0035
  30. Kanwar JR, Samarasinghe RM, Kumar K, et al. Drug Des Devel Ther. 2015;9:2927-2940. doi:10.2147/DDDT.S77369
  31. Bhujade AM, Talmale S, Kumar N, et al. J Ethnopharmacol. 2012;141(3):989-996. doi:10.1016/j.jep.2012.03.044
  32. Kumar R, Gupta YK, Singh S, Arunraja S. J Ethnopharmacol. 2015;175:346-355. doi:10.1016/j.jep.2015.08.058
  33. Blain EJ, Ali AY, Duance VC. Phytother Res. 2010;24(6):905-912. doi:10.1002/ptr.3055
  34. Verhoff M, Seitz S, Paul M, et al. J Nat Prod. 2014;77(6):1445-1451. doi:10.1021/np500198g
  35. Igarashi M, Sakamoto K, Nagaoka I. Int J Mol Med. 2011;28(3):373-379. doi:10.3892/ijmm.2011.686
  36. Simon RR, Marks V, Leeds AR, Anderson JW. Diabetes Metab Res Rev. 2011;27(1). doi:10.1002/dmrr.1150
  37. Swann DA, Radin EL, Nazimiec M, Weisser PA, Curran N, Lewinnek GE. Ann Rheum Dis. 1974;33 4:318-326.
  38. Responte DJ, Natoli RM, Athanasiou KA. J R Soc Interface. 2012;9(77):3564-3573. doi:10.1098/rsif.2012.0399
  39. Nielsen FH. Environ Health Perspect. 1994;102 Suppl(Suppl 7):59-63. doi:10.1289/ehp.94102s759 
  40. MAHY BWJ, COX NJ, ARMSTRONG SJ, BARRY RD. Nat New Biol. 1973;243(127):172-174. doi:10.1038/newbio243172a0
  41. Travers RL, Rennie GC, Newnham RE. J Nutr Med. 1990;1(2). doi:10.3109/13590849009003147
  42. Armstrong TA, Spears JW, Crenshaw TD, Nielsen FH. J Nutr. 2000;130(10). doi:10.1093/jn/130.10.2575
  43. Meacham SL, Taper LJ, Volpe SL. In: Environmental Health Perspectives. Vol 102. ; 1994. doi:10.1289/ehp.94102s779
  44. Pietrzkowski Z, Phelan MJ, Keller R, Shu C, Argumedo R, Reyes-Izquierdo T. Clin Interv Aging. 2014;9:895-899. doi:10.2147/CIA.S64590
  45. Price AK, de Godoy MRC, Harper TA, et al. J Anim Sci. 2017;95(7). doi:10.2527/jas.2017.1588
  46. Nielsen FH. J Trace Elem Exp Med. 1996;9(4):215-229. doi:10.1002/(SICI)1520-670X(1996)9:4<215::AID-JTRA7>3.0.CO;2-P
  47. Nielsen FH. J Trace Elem Med Biol. 2014;28(4):383-387. doi:10.1016/j.jtemb.2014.06.023
  48. Osipyants AI, Poloznikov AA, Smirnova NA, et al. Biochimie. 2018;147:46-54. doi:10.1016/j.biochi.2017.12.011
  49. Coassin M, Ursini F, Bindoli A. Arch Biochem Biophys. 1992;299(2). doi:10.1016/0003-9861(92)90282-2
  50. Benevolenskaia LI, Toroptsova N V, Nikitinskaia OA, et al. Ter Arkh. 2004;76(11):88-93.
  51. Leffler CT, Philippi AF, Leffler SG, Mosure JC, Kim PD. Mil Med. 1999;164(2):85-91.
  52. Sophia Fox AJ, Bedi A, Rodeo SA. Sports Health. 2009;1(6):461-468. doi:10.1177/1941738109350438
  53. Thiers H, Normand C. Rhumatologie. 1971;23(5):159-160.
  54. Thiers MH. J Med Lyon. 1972;53(222):195-198.
  55. Sen MK, Dash BK. Int J Green Pharm. 2012;6(3):169-173. doi:10.4103/0973-8258.104924

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

What Our Customers Are Saying

Our labels are clean, transparent, and exceed industry requirements.

  • Non-GMO Verified*

    * Only Where Indicated

  • Gluten Free

  • No Artificial Coloring& Flavoring

  • Science Backed