CISSUS

Cissus quadrangularis Linn. is a traditional Indian herb with well-documented beneficial effects both on the joints and the underlying bone tissue^1,2.*

Our extract provides a high concentration of ketosterones, which support optimum joint health and normal comfort in movement¹.* Cissus consists of flavonoids (quercetin, daidzein and genistein), triterpenoids (friedelin), vitamin C, iridoids and phytosterols like β- sitosterol and calcium. Scientific studies demonstrate that cissus and boswellia constituents affect key enzymes involved in the maintenance of healthy tissues^1,2-5,7,8.* Through these mechanisms, they may help support the state of comfort in the joints through the typical wear and tear of everyday life.* Due to the high concentration of vitamin C, Cissus quandrangularis Linn. is also known for its powerful antioxidant effect⁹.*

1. Bloomer RJ, Farney TM, McCarthy CG, Lee S-R. Phys Sportsmed. 2013;41(3):29-35. doi:10.3810/psm.2013.09.2021
2. Sen MK, Dash BK. Int J Green Pharm. 2012;6(3):169-173. doi:10.4103/0973-8258.104924
3. Vishal AA, Mishra A, Raychaudhuri SP. Int J Med Sci. 2011;8(7):615-622.
4. Sengupta K, Krishnaraju A V, Vishal AA, et al. Int J Med Sci. 2010;7(6):366-377.
5. Nie TW, Shukkoor MSA, Nair RS, Amiruddin FKB, Ramasamy S. J Basic Clin Physiol Pharmacol. 2015;26(1):35-41. doi:10.1515/jbcpp-2014-0035
6. Kanwar JR, Samarasinghe RM, Kumar K, et al. Drug Des Devel Ther. 2015;9:2927-2940. doi:10.2147/DDDT.S77369
7. Kumar R, Gupta YK, Singh S, Arunraja S. J Ethnopharmacol. 2015;175:346-355. doi:10.1016/j.jep.2015.08.058
8. Blain EJ, Ali AY, Duance VC. Phytother Res. 2010;24(6):905-912. doi:10.1002/ptr.3055
9. EFSA Panel on Dietetic Products N and A (NDA). EFSA J. 2010;7(1924):1-28. doi:10.2903/j.efsa.2009.1226.