Diosmin and Hesperidin are naturally-occurring flavonoids, which can be found in citrus rinds. Widely used in Europe, where they have been clinically studied, Diosmin and Hesperidin have been shown to help maintain blood vessel tone and support healthy leg circulation and capillary permeability.* Diosmin and Hesperidin also possess antioxidant properties and have been shown to positively impact healthy function of venous valves.* Diosmin supports microcirculation and strengthens blood vessels.* Hesperidin helps strengthen blood vessels and enhances the integrity of collagen.* 

​​​​​​​Collagen and Elastin peptides are the building elements of the venous wall, which helps promote strong blood vessels*. In arteries and veins they account for more than half of the vessel wall mass.

Collagen is the most abundant protein in our body, summing up for about one-third of its protein composition. It builds our hair, skin, cartilage, ligaments, etc. and together with elastin peptides provide strength and elasticity to our body.*

Elastin is an essential part of the connective tissue – it is highly elastic and helps the vessels to resume their shape after stretching or contracting. Studies indicate its beneficial effect on healthy veins.*