Avocado-soybean unsaponifiables (ASU) are a specific lipid fraction obtained by a two-step extraction process from avocado fruit and soy beans (one-third avocado oil, two-thirds soybeans oil).

Avocado oil contains polyols, sterols, long-chain saturated hydrocarbons, squalene, and tocopherols, while the key constituents in soybean oil are mainly sterols, tocopherols, terpene alcohols, methylsterols, squalene, saturated hydrocarbons, and aliphatic alcohols.

ASU is reported to exert beneficial effect on normal antioxidant function of chondrocytes, thus supporting the normal flexibility of the joints1.* Many studies suggest that ASU may also help natural collagen synthesis, supporting normal joint movement2.*

The beneficial properties of ASU were first discovered in 1955 by Prof. Henri Thiers, a pioneer in its clinical trials. During continuous years of research, Prof. Thiers succeeded in proving both short-term and long-term effect of ASU for the normal function of joints3,4.*

  1. Au RY, Al-Talib TK, Au AY, Phan P V, Frondoza CG. Osteoarthritis Cartilage. 2007;15(11):1249-1255. doi:10.1016/j.joca.2007.07.009
  2. Christiansen BA, Bhatti S, Goudarzi R, Emami S. Cartilage. 2015;6(1):30-44. doi:10.1177/1947603514554992
  3. Thiers H, Normand C. Rhumatologie. 1971;23(5):159-160.
  4. Thiers MH. J Med Lyon. 1972;53(222):195-198.


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