SHIITAKE MUSHROOM EXTRACT

Shiitake is one of the most studied mushrooms today. Part of the millennial Eastern herbalist tradition, it’s used to support the body's normal immune function^1-5.*

Shiitake extract contains a complex of alpha and beta-glucans, and several types of polysaccharides that have positive effects on innate immune cells^6,7.* Shiitake mushroom is also a valuable source of vitamins – especially provitamin D2, vitamins B1, B2, B12 and pantothenic acid - as well as minerals Fe, Mn, K, Ca, Mg, Cu, P, and Zn. Shiitake has been a subject of many studies that prove its beneficial effect on a healthy immune response^1-5.* The most-studied beta-glucan in Shiitake mushroom is lentitan, which has been proven to help maintain the function of immune cells⁷.*

1. Morales D, Rutckeviski R, Villalva M, et al. Carbohydr Polym. 2020;229:115521. doi:https://doi.org/10.1016/j.carbpol.2019.115521
2. Dai X, Stanilka JM, Rowe CA, et al. J Am Coll Nutr. 2015;34(6):478-487. doi:10.1080/07315724.2014.950391
3. Zembron-Lacny A, Gajewski M, Naczk M, Siatkowski I. J Physiol Pharmacol an Off J Polish Physiol Soc. 2013;64(2):249-254.
4. Gaullier J-M, Sleboda J, Ofjord ES, et al. Int J Med Mushrooms. 2011;13(4):319-326.
5. Spierings ELH, Fujii H, Sun B, Walshe T. J Nutr Sci Vitaminol (Tokyo). 2007;53(6):536-539. doi:10.3177/jnsv.53.536
6. Gaullier J-M, Sleboda J, Ofjord ES, et al. Int J Med Mushrooms. 2011;13(4):319-326.
7. Kupfahl C, Geginat G, Hof H. Int Immunopharmacol. 2006;6(4):686-696. doi:10.1016/j.intimp.2005.10.008